All protocols

Goal Protocol

Anti-Aging

A conservative longevity track focused on mitochondrial function, sleep, immune tone and measurable healthspan markers.

Longevity is a slow game played with fast tools. This protocol is deliberately conservative — it prioritises interventions with real biological rationale, measurable markers and decades-long safety data, not headline-chasing molecules.

The focus is on the systems that age first and drag the rest with them: mitochondrial output, immune tone, sleep architecture, glucose control and inflammation. Epithalon and mitochondrial peptides (MOTS-c, SS-31, MQ-NAD-C) address the machinery of energy production, while Thymosin Alpha-1 supports immune regulation.

Nothing here promises to reverse aging. The point is to compress morbidity — to keep the last decades of life as functional as the first — using tools with a plausible mechanism and a monitoring plan.

Mitochondria
Immune tone
Healthspan markers
Molecules to review
How this protocol works

Epithalon appears to modulate telomerase and pineal function, supporting sleep and circadian rhythm. MOTS-c and SS-31 act at the mitochondrial membrane to improve ATP output and reduce oxidative stress. MQ-NAD-C replenishes the NAD+ pool that fuels sirtuins and DNA repair. Thymosin Alpha-1 tunes immune activity toward regulation rather than chronic low-grade inflammation.

Protocol phases
Phase 1
Baseline (weeks 0–4)

Comprehensive labs, body composition, VO2 estimate, sleep and HRV baseline. Lock in the non-negotiables — sleep, protein, strength training — before adding molecules.

Phase 2
Intervention (weeks 4–20)

Introduce one peptide at a time in short cycles. Recheck labs and subjective markers at week 12 to isolate what is actually helping.

Phase 3
Long-term rotation (weeks 20+)

Cycle molecules with off-periods; keep the lifestyle base constant. Reassess biomarkers every six months.

Lifestyle foundations
Zone 2 cardio

Three to four sessions of low-intensity aerobic work weekly to build mitochondrial density.

Strength training

Twice-weekly resistance training preserves muscle, bone and insulin sensitivity — the strongest predictor of healthy aging.

Whole-food diet

Mediterranean-style intake with emphasis on protein, olive oil, fibre and polyphenols; minimise ultra-processed food and alcohol.

Sleep and social connection

Two under-rated longevity levers — protect both like medication.

What to expect

Subjective changes (sleep quality, recovery, energy) often appear within four to eight weeks. Biomarker shifts — hs-CRP, HbA1c, lipid ratios — become visible over 12–24 weeks. This is a slow-return investment, not a quarterly result.

Biomarkers to track
Blood
  • CBC
  • CMP
  • hs-CRP
  • Lipid panel with ApoB
  • HbA1c and fasting insulin
  • Homocysteine
  • 25-OH vitamin D
  • IGF-1
  • DHEA-S
  • TSH
Urine
  • Urinalysis with microalbumin
  • 8-OHdG (oxidative stress, when available)
Cautions and contraindications
  • Avoid strong pro-growth interventions if there is a personal or family history of cancer.
  • Do not stack multiple novel peptides simultaneously — you lose the ability to attribute effects and side-effects.
  • Anti-aging is a supervised, monitored practice, not a self-experimentation contest.

Educational content only. Not medical advice. Speak with a qualified clinician before starting any peptide protocol.